Silicon-based Cross-coupling Reagents Gelest, manufacturer of gram to multiple-ton quantities of silane, metal organic, and silicone materials offers the widest array of organosilanes on the market, has broadened its silicon-based cross-coupling agent offerings to include aryl-, vinyl- and ethynyl silanes, which provide a non-toxic, easily handled, and economical alternative to commonly employed tin and boron cross-coupling derivatives.
Silicon-based cross-coupling agents are useful in a number of synthetic applications. They provide excellent flexibility for the formation of the carbon-carbon bond, whose strength and stability, coupled with carbons concatenation capability, enable the formation of a nearly limitless number of molecules for use in a wide range of specialty chemical applications in plastics, pharmaceuticals, electronics, and paint and coatings, among other application areas. Gelests ability to form carbon-carbon bonds through the cross-coupling of an organic halide or pseudohalide with an organometallic reagent is drawing the attention of synthetic organic chemists as well as catalyst and specialty ligand providers.
These reactions represent excellent elasticity for the formation of the carbon-carbon bond along with good functional group tolerance. One of these cross-coupling reactions – the Hiyama reaction – employs an organosilane as the organometallic partner in the cross-coupling reaction. Organosilicon and Metal-organic Materials for Renewable Energy Systems Gelest offers a wide array of organosilicon and metal-organic materials to assist scientists in the development of technologies for the generation, capture and storage of renewable energy.
Materials are available to help meet the electroactive and photoactive design challenges posed by systems and components for renewable energy generation including photovoltaic systems, fuel cells, electrodes, solid-state electrolytes, proton-conducting solids, catalysts, and wind turbines and by capture and storage components such as advanced lithium batteries and ultracapacitors.
With Gelests technical expertise, a world of formulation challenges may be addressed and solved for structural materials, including mesoporous ceramics and advanced composites; optical materials, including band-gap and index materials; electroactive and dielectric materials, including membranes, electrodes and electrolytes; component protection materials, including passivation and encapsulation; water immiscible fluids, for electrolyte, heat transfer and lubricant applications; and Sol-Gel coatings, for anti-reflection and abrasion resistance.
Organosilane reductions made cost-effective
Many organic functional groups, ranging from carboxylic acids to aryl fluorides, may be reduced with a variety of organosilanes. The most popular is the easy-to-handle triethylsilane. However, the cost of using this organosilane can be expensive and it does not provide the most hydride for the weight.
Gelest can provide cost-effective reductions using the easy-to-handle, inexpensive and environmentally friendly polymethylhydrosiloxane (PMHS)-type materials as the reducing agent. PMHS siloxanes, in addition to costing much less than triethylsilane, carry considerably more hydride (1.35% on a molar basis) than triethylsilane (0.86% on a molar basis). PMHS reductions may be performed on olefins, aromatic and aliphatic halides, carboxylic acid and esters, aldehydes and ketones, imines, and reductive deallylation reactions. In addition, some highly useful asymmetric reductions may be performed on prochiral ketones, enones, ?,?-unsaturated esters and lactones, and imines.
For more information on the variety of advances presented by Gelest or to engage in discussions to explore viable solutions, please contact Gabrielle Horvath at ghorvath@gelest.com, or visit www.gelest.com
